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The pathophysiology of diabetes involves a defective amplification of the late-phase insulin response to glucose by glucose-dependent insulinotropic polypeptide-regardless of etiology and phenotype
Most patients experience gastrointestinal symptoms during the initial 4 weeks and following dose increases, with gradual improvement over 812 weeks
This can make it easier to notice subtle improvements and stay motivated over time
1
Weekly injections of MEDI4166 reduced body weight in a dose-dependent manner (Fig
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