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Secondly, significant weight loss and the resultant change in the inflammatory phenotype of obese adipose tissue would reduce the release into the circulation of key pro-fibrotic pro-inflammatory cytokines/adipokines such as TNF-, IL-6, leptin [31], visfatin and resistin, and increase levels of anti-fibrotic adipokines such as adiponectin [32]
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GLP-1 is a hormone naturally produced in your gut
However, research has begun to discover applications for these therapies beyond cardiometabolic health due to their systemic antiinflammatory properties
Endothelial progenitor cells dysfunctions and Cardiometabolic disorders: from mechanisms to therapeutic approaches
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