the original rodent study used 5 mg/kg, which when scaled allometrically to human equivalents suggests doses in the 5-10 mg range for a 70 kg adult, though allometric scaling from mice to humans is an imprecise science
It is only available for prescription use and is administered by injection or, in severe cases, an IV drip
In principle, these distinct entry points could produce additive AMPK activation, but this dual activation has not been formally studied in humans and warrants physician oversight, particularly regarding blood glucose monitoring
The most commonly reported are mild fatigue or lightheadedness shortly after injection, which typically resolve quickly
- IGF-1 LR3 is a research peptide analog studied in models involving IGF-1 receptor signaling, cellular growth pathways, protein synthesis research, glucose-related signaling, tissue-response models, and anabolic pathway biology