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"It's a significant decrement in the ability to taste the basic taste qualities." "Altered taste sensation, known medically as dysgeusia, is a well-known class effect for all marketed GLP-1s and has been listed in the respective prescribing information for these medicines," a spokesperson for Novo Nordisk, maker of popular GLP-1s Ozempic, Wegovy and Victoza, told USA TODAY via email

Clinical Guidance: If you are losing weight on a GLP-1, you should work closely with your GP to have your TSH and Free T4 levels checked every 812 weeks

Mechanistically, the viral interleukin-6 (vIL-6) encoded by KSHV facilitates SIRT3-mediated deacetylation of SERBP1, preventing its binding to lipoyl transferase 2 (Lipt2) mRNA and protecting it from mRNA degradation-induced ferroptosis[146]

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Interpretation should consider sex-specific reference ranges and assay variability