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Pellets avoid the daily dosing of creams and the absorption variability of oral hormones

Both activate overlapping melanocortin receptors, and concurrent use would effectively increase the total melanocortin agonist dose without adding any mechanistic benefit

If a patient has experienced a confirmed allergic reaction to exenatide (an exendin-4 derivative), switching to tirzepatide may be considered, as there is no structural overlap

Understanding that these digestive changes result from the medication's intended mechanism of actionrather than representing a malfunctioncan help patients manage expectations

Cravings may feel stronger Ozempic and Mounjaro can reduce cravings and make highly rewarding foods feel less tempting