Additionally, underlying sleep disorders such as obstructive sleep apnea or gastroesophageal reflux disease (GERD) may affect sleep quality in patients taking tirzepatide
These include semaglutide (Ozempic, Wegovy, Rybelsus), liraglutide (Victoza, Saxenda), dulaglutide (Trulicity), and tirzepatide (Mounjaro, Zepbound)though tirzepatide is technically a dual GIP/GLP-1 receptor agonist
It also carries cardiovascular and MASH indications
Clinicians should exercise caution in patients with a history of pancreatitis or gastroparesis, inflammatory bowel disease, other gut motility disorders, medullary thyroid carcinoma, or Multiple Endocrine Neoplasia syndrome type 2, and pause therapy when clinically indicated, such as before anesthesia
Differences in gut microbiota associated with age, sex, and stool consistency in healthy Japanese subjects