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The Regents of the University of Michigan.
Practical Implications of No IGF-1 Elevation: The absence of IGF-1 stimulation makes AOD-9604 suitable for populations who need to avoid IGF-1 elevation, including individuals with personal or family history of hormone-sensitive cancers, those concerned about accelerated aging through growth pathway activation, people seeking fat loss without anabolic muscle-building effects, individuals who have contraindications to growth hormone therapy, and those undergoing screening or monitoring where IGF-1 elevation would be problematic
(Over the course of several months, Undark sent numerous messages to Sikiric
Such direct inhibitory action appears surprising for a peptide thought to be primarily involved in sleep promotion