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The temporal behavior of the concentration of ROS is described with the equation ROS is created due to photo-oxidation and other factors that are not part of glucose metabolism (represented by r ) 15,17
Since most chemotherapeutic agents increase intracellular ROS levels [47], TIC resistance may stem from their high antioxidant content, including glutathione
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A few practical takeaways from this list: DOD is the biggest funder but has the most opaque process
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