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8.9% with placebo.[1,4] During the trial, gastrointestinal adverse events were more frequent in the semaglutide group than in the placebo group

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Furthermore, the trajectory of the weight loss curves suggested that at 48 weeks the plateau of weight was not yet reached and all the participants in the 8 and 12 mg had a weight reduction of 5% or more, which is currently the minimum threshold for efficacy [64]