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The main mechanism of trimetazidine is modulating mitochondrial energy production [117]
PMID: 29263482
NICE guidelines for weight management emphasise evidence-based interventions including dietary modification, increased physical activity, behavioural therapy, and in appropriate cases, pharmacological treatments (such as orlistat or semaglutide) or bariatric surgery
Consistently, compounds like SFN are known to cause G2/M cell cycle arrest in various cancer cell lines, thereby suppressing tumor growth (113)
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