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Nonetheless, individuals with a personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia type 2 (MEN2) should discuss this with their clinician before enrolling in any trial involving this class of agent
Apperloo EM, Neuen BL, Fletcher RA, Jongs N, Anker SD, Bhatt DL, et al
Moreover, it is effective for patients with weight-related issues such as type 2 diabetes, high cholesterol, or high blood pressure
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However, both compounds elevate sympathetic tone cagrilintide indirectly via vagal signalling, tesofensine directly via norepinephrine reuptake inhibition so cardiovascular monitoring would be essential
