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Common GLP-1 Side Effects According to clinical literature and FDA labeling for approved GLP-1 medications, commonly reported side effects include nausea (especially when starting or after dose increases), vomiting, diarrhea, constipation, abdominal discomfort, decreased appetite, fatigue, and injection site reactions (for injectables)
doi: 10.1016/j.enceco.2025.06.014 8 LiXJingKSongPYuJ
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