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10.1007/s12016-017-8631-6 Clin Rev Allergy Immunol
Animal studies show that bacopa may be effective in reversing the anxiety that comes from abstaining from alcohol in regular drinkers.[ref] Magnolia bark extract: Magnolia bark extract contains a polyphenol called honokiol
doi:10.1158/1078-0432.CCR-08-1930
Treated mice showed improved Morris water maze performance reduced escape latency emerging across roughly days 45 of the training protocol alongside increased synaptophysin and reduced inflammatory markers (IL-1, TNF-), reportedly via PI3K/AKT signaling
That said, some preclinical research has explored oral BPC-157 in the context of gastrointestinal health, where localized gut exposure may be relevant
