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We're extrapolating from robust data in similar tissue types
E.Mondragn-GuillnM.Tavira-MontalvanC
Blood cell telomere length is a dynamic feature
Karimani A, Ramezani N, Afkhami Goli A, Nazem Shirazi MH, Nourani H, Jafari AM
To further verify that the catalytic activity of LOXL2 was responsible for the increase in BHZ signal, we used the following negative controls: (1) the overexpression of catalytically inactive H626/628Q LOXL2 double mutant (LOXL2-DM) 39,40 , (2) inhibition of LOXL2 specific activity using the small molecule inhibitor PAT-1251 (10 M) in cells overexpressing catalytically active LOXL2 41 , and (3) inhibition of total LOX activity using the non-selective small molecule LOX inhibitor -Aminopropionitrile (BAPN
