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They are distinct challenges with distinct solutions
Hsing CH and colleagues demonstrated that cisplatin robustly activated glycogen synthase kinase-3 (GSK-3) in vivo within the kidneys and in vitro in PTEC, leading to elevated cytokine/chemokine production, as well as the infiltration of inflammatory immune cells such as neutrophils, monocytes/macrophages, and T lymphocytes [117]
Aye S, Johansson G, Hock C et al (2025) Point of view: challenges in implementation of new immunotherapies for Alzheimers disease
[10] Using the correct volume ensures the medication is properly dissolved or diluted and delivered at the intended dose
10.1016/j.jhep.2013.08.011 J
